Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044670 | 0.93 | KCNH2 (0.37) | CYP2C9CYP2C19CYP3A4KCNH2RAB9A | |
| SCHEMBL31045068 | 0.92 | NPC1 (0.35) | CYP2C9CYP2C19CYP3A4KCNH2RAB9A | |
| SCHEMBL31044954 | 0.90 | MCHR1 (0.34) | KCNH2RAB9ANPC1GALR3NR2F2 | |
| SCHEMBL31045314 | 0.88 | CYP3A4 (0.37) | CYP2C9CYP2C19CYP3A4KCNH2RAB9A | |
| SCHEMBL31044917 | 0.85 | CYP3A4 (0.36) | CYP2C9CYP2C19CYP3A4KCNH2RAB9A | |
| SCHEMBL31044928 | 0.85 | RAB9A (0.35) | CYP2C9CYP2C19CYP3A4KCNH2RAB9A | |
| SCHEMBL31044674 | 0.84 | MCHR1 (0.38) | KCNH2RAB9ANPC1GALR3NR2F2 | |
| SCHEMBL31045149 | 0.82 | KCNH2 (0.36) | CYP2C9CYP2C19CYP3A4KCNH2RAB9A | |
| SCHEMBL31044854 | 0.82 | KCNH2 (0.41) | CYP3A4KCNH2RAB9ANPC1GALR3 | |
| SCHEMBL31045035 | 0.81 | GBA1 (0.39) | CYP2C19CYP2D6CYP1A2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | FIMBRION THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | G6PD, SDHA, NQO1 | CYP2C9 2771/4885CYP2C19 3009/4885CYP3A4 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.