Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486687 | 1.00 | CRHBP (0.52) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL8810869 | 0.82 | HCAR3 (0.68) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL1558414 | 0.81 | CRHBP (0.48) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL303646 | 0.78 | MAPT (0.63) | CRHBPCRHR2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL29351451 | 0.78 | MAPT (0.63) | CRHBPCRHR2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10089736 | 0.75 | CRHBP (0.68) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL8673641 | 0.74 | HCAR3 (0.66) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL2717483 | 0.74 | CRHBP (0.46) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL9140856 | 0.74 | CRHBP (0.60) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| Ethylamine SCHEMBL5152975 | 0.74 | MAPT (0.50) | MAPTMAPK1TDP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182425-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASES/DISORDERS | NOUREDDINE ACHRAF (US) | 2024-09-06 | — | — | WO | disclosed |