Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 16/20 | 0.71 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242652 | 0.91 | APP (0.54) | APPNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL6388039 | 0.91 | APP (0.54) | APPNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL31453872 | 0.85 | APP (0.48) | APPNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL18429785 | 0.84 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL2849932 | 0.84 | APP (0.59) | APPNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL24742460 | 0.82 | MAOB (0.61) | APPNPC1RAB9A | |
| SCHEMBL10226406 | 0.82 | RXRA (0.54) | APPRXRARXRBNPC1CASP3 | |
| SCHEMBL8621941 | 0.82 | RAB9A (0.59) | APPNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL21244006 | 0.82 | APP (0.61) | APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13899704 | 0.82 | NPC1 (0.64) | APPNPC1CASP3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496409-A | Caliper [3] acridine polymer and preparation method and application thereof | 中国科学院化学研究所 | 2024-08-16 | — | — | CN | disclosed |