Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | WRN | Q14191 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035250 | 0.86 | ACHE (0.44) | ACHEWRNGAAALDH1A1KMT2A | |
| SCHEMBL30037179 | 0.86 | ACHE (0.44) | ACHEWRNGAAALDH1A1KMT2A | |
| SCHEMBL31270593 | 0.86 | WRN (0.41) | ACHEWRNGAAALDH1A1TSHR | |
| SCHEMBL31047182 | 0.85 | WRN (0.50) | ACHEWRNGAAALDH1A1KMT2A | |
| SCHEMBL31499632 | 0.84 | WRN (0.45) | ACHEWRNALDH1A1KMT2AMEN1 | |
| SCHEMBL30038447 | 0.83 | WRN (0.61) | ACHEWRNGAAALDH1A1TSHR | |
| SCHEMBL25036852 | 0.83 | WRN (0.61) | ACHEWRNGAAALDH1A1TSHR | |
| SCHEMBL31295764 | 0.83 | WRN (0.49) | ACHEWRNALDH1A1TSHRHSD17B10 | |
| SCHEMBL31295794 | 0.83 | WRN (0.49) | ACHEWRNGAAALDH1A1KMT2A | |
| SCHEMBL31295756 | 0.83 | WRN (0.47) | ACHEWRNALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024193716-A1 | TRIAZOLOPYRIMIDINE COMPOUND | 南京再明医药有限公司 | 2024-09-26 | — | — | WO | disclosed |