Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270578 | 0.87 | WRN (0.48) | WRNACHEAKR1B1NTRK1MAPT | |
| SCHEMBL31499786 | 0.86 | WRN (0.51) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL31047165 | 0.85 | ACHE (0.47) | WRNACHEKMT2AALDH1A1MEN1 | |
| SCHEMBL25037213 | 0.84 | WRN (0.69) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL30037138 | 0.84 | WRN (0.69) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL31295799 | 0.83 | WRN (0.56) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL31295837 | 0.83 | WRN (0.54) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL31295828 | 0.83 | WRN (0.54) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL31295752 | 0.83 | WRN (0.62) | WRNACHEAKR1B1KMT2AALDH1A1 | |
| SCHEMBL31295768 | 0.83 | WRN (0.56) | WRNACHEAKR1B1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024193716-A1 | TRIAZOLOPYRIMIDINE COMPOUND | 南京再明医药有限公司 | 2024-09-26 | — | — | WO | disclosed |