Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104132 | 0.87 | PIK3CA (0.44) | CNR1CNR2TDP1S1PR2MGLL | |
| SCHEMBL29248610 | 0.87 | LMNA (0.51) | CNR1CNR2SMN1; SMN2TDP1GRM1 | |
| SCHEMBL25153864 | 0.87 | LMNA (0.51) | CNR1CNR2SMN1; SMN2TDP1GRM1 | |
| SCHEMBL31015715 | 0.86 | CNR1 (0.38) | CNR1CNR2SMN1; SMN2TDP1GRM1 | |
| SCHEMBL31165558 | 0.84 | HRH4 (0.49) | MGLLMEN1KMT2ANPSR1HRH3 | |
| SCHEMBL31165380 | 0.81 | C5AR1 (0.35) | CNR1CNR2SMN1; SMN2TDP1NPC1 | |
| SCHEMBL31165292 | 0.78 | KDM1A (0.44) | TDP1KMT2A | |
| SCHEMBL21448788 | 0.78 | CNR1 (0.59) | CNR1CNR2SMN1; SMN2MGLLMEN1 | |
| SCHEMBL18031383 | 0.78 | VCP (0.43) | S1PR2MGLL | |
| SCHEMBL12788104 | 0.77 | TAS1R3 (0.50) | GRM1MGLLHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024193689-A1 | PYRIDINOPYRROLE DERIVATIVE AND USE THEREOF IN DRUGS | 广东东阳光药业股份有限公司 | 2024-09-26 | — | — | WO | disclosed |
| CN-118684665-A | Pyridopyrrole derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-09-24 | — | — | CN | disclosed |