SCHEMBL31047321

SCHEMBL31047321

O=C(Nc1cccc2nc(N3CC(F)(F)C3)cnc12)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748572 0.85 KIF18A (0.70) KIF18A
SCHEMBL26650648 0.85 KIF18A (0.70) KIF18A
SCHEMBL27455493 0.82 KIF18A (0.76) KIF18A
SCHEMBL31613813 0.81 KIF18A (0.67) KIF18A
SCHEMBL31047341 0.80 KIF18A (0.72) KIF18A
SCHEMBL22964485 0.80 KIF18A (1.00) KIF18A
SCHEMBL29607790 0.80 KIF18A (1.00) KIF18A
SCHEMBL22122467 0.80 KIF18A (1.00) KIF18A
SCHEMBL27455593 0.80 KIF18A (0.78) KIF18A
SCHEMBL31047333 0.79 KIF18A (0.71) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149189-A1 AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2024-07-18 — — WO disclosed
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