Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882986 | 0.80 | PTPN11 (0.36) | CRBNPTPN11HCRTR2SMN1; SMN2GRM2 | |
| SCHEMBL31047340 | 0.72 | IDH1 (0.37) | SMN1; SMN2OPRM1OPRD1SMO | |
| SCHEMBL31047342 | 0.72 | IDH1 (0.37) | SMN1; SMN2OPRM1OPRD1SMO | |
| SCHEMBL31047358 | 0.71 | KIF18A (0.47) | — | |
| SCHEMBL31122306 | 0.66 | GRM2 (0.39) | KCNH2GRM2 | |
| SCHEMBL5448072 | 0.66 | PRMT5 (0.64) | MAOB | |
| SCHEMBL2085938 | 0.66 | SMN1; SMN2 (0.53) | SMN1; SMN2KCNH2GRM2HSD11B1 | |
| SCHEMBL12472367 | 0.65 | PRMT5 (0.38) | SMN1; SMN2KCNH2GRM2 | |
| SCHEMBL29496124 | 0.65 | GAA (0.43) | PDE10A | |
| SCHEMBL28722181 | 0.65 | GAA (0.43) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |