SCHEMBL31047354

SCHEMBL31047354

O=C(Nc1cccc2ncc(N3CC(F)(F)C3)nc12)c1ccc(Br)cc1N1CCC2(CC1)CC2

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31047324 0.83 KIF18A (0.48) KIF18A
SCHEMBL31047321 0.78 KIF18A (0.66) KIF18A
SCHEMBL31047339 0.76 KIF18A (0.51) KIF18A
SCHEMBL31047358 0.76 KIF18A (0.47) KIF18A
SCHEMBL22964659 0.76 KIF18A (0.68) KIF18A
SCHEMBL29578239 0.76 KIF18A (0.68) KIF18A
SCHEMBL22122479 0.76 KIF18A (0.75) KIF18A
SCHEMBL24318989 0.74 KIF18A (0.70) KIF18A
SCHEMBL29609024 0.74 KIF18A (0.70) KIF18A
SCHEMBL22152322 0.73 KIF18A (0.69) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149189-A1 AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2024-07-18 — — WO disclosed
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