Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18943573 | 0.81 | BCHE (0.46) | TYMPKDM4EGAAALPLPARP1 | |
| SCHEMBL31047669 | 0.75 | SERPINE1 (0.65) | TYMPKDM4EGAAPARP1SERPINE1 | |
| SCHEMBL31047686 | 0.74 | PDE9A (0.44) | KDM4EGAASERPINE1TNKSTNKS2 | |
| SCHEMBL31047682 | 0.72 | SERPINE1 (0.51) | KDM4EPARP1SERPINE1MEN1TNKS | |
| SCHEMBL31047681 | 0.71 | SERPINE1 (0.50) | KDM4EGAAPARP1SERPINE1MEN1 | |
| SCHEMBL8220603 | 0.71 | ALDH1A1 (0.53) | TYMPKDM4EGAAALPLPARP1 | |
| SCHEMBL31047696 | 0.70 | SERPINE1 (0.69) | KDM4EPARP1SERPINE1PDE10AMEN1 | |
| SCHEMBL31047695 | 0.70 | PARP1 (0.49) | PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL31047685 | 0.70 | SERPINE1 (0.69) | KDM4EGAAPARP1SERPINE1MEN1 | |
| SCHEMBL18943341 | 0.69 | CA1 (0.37) | PARP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |