Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048018 | 0.88 | PIM1 (0.41) | EHMT2PIM1PIM2ALDH1A1USP30 | |
| SCHEMBL31048004 | 0.88 | PIM1 (0.41) | EHMT2PIM1PIM2ALDH1A1USP30 | |
| SCHEMBL31178709 | 0.82 | PDE4B (0.43) | NR1H2GPR119SSTR4PDE4B | |
| SCHEMBL16834214 | 0.81 | NR1H2 (0.45) | NR1H2EHMT2PIM1PIM2ALDH1A1 | |
| SCHEMBL30849213 | 0.80 | ALDH1A1 (0.47) | NR1H2ALDH1A1GPR119USP30NPC1 | |
| SCHEMBL25191571 | 0.78 | GPR119 (0.50) | NR1H2EHMT2ALDH1A1GPR119USP30 | |
| SCHEMBL30234604 | 0.78 | GPR119 (0.50) | NR1H2EHMT2ALDH1A1GPR119USP30 | |
| SCHEMBL31358059 | 0.78 | USP30 (0.45) | NR1H2PIM1PIM2ALDH1A1GPR119 | |
| SCHEMBL24157379 | 0.78 | NR1H2 (0.49) | NR1H2ALDH1A1GPR119MAPT | |
| SCHEMBL30297083 | 0.78 | NR1H2 (0.49) | NR1H2ALDH1A1GPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178125-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-08-29 | — | — | WO | disclosed |