SCHEMBL31048907

SCHEMBL31048907

O=C(CBr)Nc1ccc(Cl)cc1C(=O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.69
MAPT P10636 7/20 0.65
TP53 P04637 3/20 0.65
ALDH1A1 P00352 5/20 0.64
LMNA P02545 4/20 0.64
POLB P06746 2/20 0.63
MEN1 O00255 1/20 0.63
MAPK1 P28482 1/20 0.63
KMT2A Q03164 1/20 0.63
KDM4E B2RXH2 1/20 0.63
HTT P42858 1/20 0.62
THRB P10828 1/20 0.62
GAA P10253 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11538033 1.00 SMN1; SMN2 (0.69) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL11452911 0.89 MAPT (0.63) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL30661080 0.87 ALDH1A1 (0.71) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL16922182 0.87 ALDH1A1 (0.71) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL5418944 0.87 ALDH1A1 (0.71) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL11729355 0.86 SMN1; SMN2 (0.69) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL29769836 0.86 SMN1; SMN2 (0.69) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL13263480 0.85 SMN1; SMN2 (0.71) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL11659841 0.85 SMN1; SMN2 (0.71) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL10813064 0.85 GABRP (0.76) SMN1; SMN2MAPTTP53ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359535-A Synthesis method of N-tert-butoxycarbonyl-3-pyridyl-D/L-alanine 武汉理工大学 2024-07-19 CN disclosed