SCHEMBL31049299

SCHEMBL31049299

Fc1cc(SCc2ccccc2)cn2c(-c3nnc(C(F)F)o3)cnc12

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 15/20 0.43
EGFR P00533 2/20 0.37
NPSR1 Q6W5P4 1/20 0.33
HDAC1 Q13547 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049363 0.82 HDAC6 (0.43) HDAC6EGFR
SCHEMBL30967346 0.79 MEN1 (0.32)
SCHEMBL29267244 0.76 HDAC6 (0.42) HDAC6
SCHEMBL31049397 0.75 HDAC6 (0.35) HDAC6
SCHEMBL30967347 0.72 ALDH1A1 (0.39)
SCHEMBL31049551 0.71 HDAC6 (0.37) HDAC6
SCHEMBL30967342 0.70 MAPT (0.36)
SCHEMBL31049321 0.69 EGFR (0.39) EGFRNPSR1
SCHEMBL29267287 0.69 TERT (0.31)
SCHEMBL30713247 0.69 TERT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173453-A1 HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS IDEAYA BIOSCIENCES, INC. (US) 2024-08-22 WO disclosed