Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401906 | 0.81 | L3MBTL1 (0.38) | ALDH1A1RAB9ANPC1KMT2AL3MBTL1 | |
| SCHEMBL12267661 | 0.81 | L3MBTL1 (0.38) | ALDH1A1RAB9ANPC1KMT2AL3MBTL1 | |
| SCHEMBL22271023 | 0.80 | PLAU (0.50) | ALDH1A1RAB9ANPC1KMT2AL3MBTL1 | |
| SCHEMBL19760999 | 0.80 | L3MBTL1 (0.36) | ALDH1A1RAB9ANPC1KMT2AL3MBTL1 | |
| SCHEMBL30450482 | 0.80 | L3MBTL1 (0.36) | ALDH1A1RAB9ANPC1KMT2AL3MBTL1 | |
| SCHEMBL31200216 | 0.72 | PLAU (0.38) | PLAU | |
| SCHEMBL26664362 | 0.72 | PLAU (0.38) | PLAU | |
| SCHEMBL16897366 | 0.72 | OPRK1 (0.43) | — | |
| SCHEMBL16897365 | 0.72 | OPRK1 (0.43) | — | |
| SCHEMBL24007348 | 0.71 | PLAU (0.38) | RAB9AKMT2AHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173453-A1 | HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2024-08-22 | — | — | WO | disclosed |