Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12267661 | 1.00 | L3MBTL1 (0.38) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL19760999 | 0.81 | L3MBTL1 (0.36) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL22271023 | 0.81 | PLAU (0.50) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL30450482 | 0.81 | L3MBTL1 (0.36) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL31049459 | 0.81 | ALDH1A1 (0.38) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL13017447 | 0.79 | L3MBTL1 (0.38) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL5624489 | 0.74 | CYP1A2 (0.38) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL5624486 | 0.74 | CYP1A2 (0.38) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL21572724 | 0.74 | HSD17B10 (0.37) | L3MBTL1HTTMAPTMAPK1HSD17B10 | |
| SCHEMBL32662109 | 0.74 | HSD17B10 (0.37) | L3MBTL1HTTMAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224438-A1 | NOVEL PROCESS FOR THE MANUFACTURE OF 5-HALOGENATED-7-AZAINDOLES | HOFFMANN-LA ROCHE, INC. | 2011-09-15 | — | — | US | disclosed |
| WO-2011109932-A1 | NOVEL PROCESS FOR THE MANUFACTURE OF 5-HALOGENATED-7-AZAINDOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224438-A1 | NOVEL PROCESS FOR THE MANUFACTURE OF 5-HALOGENATED-7-AZAINDOLES | AZI2, UGT2B7, CYP3A5 | L3MBTL1 3681/4885HTT 2648/4885MAPT 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.