Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049393 | 0.86 | ICMT (0.41) | ALDH1A1PLAUELANEGAAHTT | |
| SCHEMBL31049268 | 0.76 | ALDH1A1 (0.36) | ALDH1A1PLAUELANEGAAHTT | |
| SCHEMBL31049571 | 0.76 | ALDH1A1 (0.36) | ALDH1A1PLAUELANEGAAHTT | |
| SCHEMBL31049356 | 0.76 | CNR2 (0.47) | ALDH1A1GAAHTTHPGDKMT2A | |
| SCHEMBL31049311 | 0.75 | CNR2 (0.37) | ALDH1A1HPGDPOLBLMNAMAPK1 | |
| SCHEMBL31049305 | 0.72 | PLAU (0.34) | ALDH1A1PLAUELANEGAAHTT | |
| SCHEMBL31049379 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HPGDTSHRLMNAMAPK1 | |
| SCHEMBL27032359 | 0.69 | HPGD (0.38) | ALDH1A1HPGDPOLBTSHRLMNA | |
| SCHEMBL27032021 | 0.68 | SMN1; SMN2 (0.45) | ALDH1A1RAB9AHPGDTSHRLMNA | |
| SCHEMBL27077566 | 0.68 | ALDH1A1 (0.37) | ALDH1A1HTTRAB9AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |