Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049311 | 0.89 | CNR2 (0.37) | CNR2ALDH1A1HPGDKMT2AJAK3 | |
| SCHEMBL31049393 | 0.86 | ICMT (0.41) | CNR2ALDH1A1GAAHPGDHTT | |
| SCHEMBL31049268 | 0.85 | ALDH1A1 (0.36) | CNR2ALDH1A1GAAHPGDHTT | |
| SCHEMBL31049571 | 0.83 | ALDH1A1 (0.36) | CNR2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL31049305 | 0.81 | PLAU (0.34) | CNR2ALDH1A1KDM4EGAAHTT | |
| SCHEMBL31049532 | 0.76 | ALDH1A1 (0.36) | CNR2ALDH1A1GAAHPGDHTT | |
| SCHEMBL31049388 | 0.74 | MEN1 (0.33) | CDK2CDK9HDAC1HDAC6HDAC3 | |
| SCHEMBL31049581 | 0.68 | IP6K1 (0.33) | — | |
| SCHEMBL22994867 | 0.68 | CYP19A1 (0.45) | CNR2HASPINALDH1A1KDM4EGLA | |
| SCHEMBL31049503 | 0.67 | AR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |