Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049622 | 0.77 | ELANE (0.31) | ELANE | |
| SCHEMBL31049600 | 0.73 | RAB9A (0.32) | — | |
| SCHEMBL31049557 | 0.70 | MAPT (0.30) | MAPT | |
| SCHEMBL31049656 | 0.70 | MTNR1A (0.31) | — | |
| SCHEMBL18502839 | 0.70 | — | — | |
| SCHEMBL844311 | 0.69 | — | — | |
| SCHEMBL23612391 | 0.65 | ALDH1A1 (0.46) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL23244419 | 0.64 | KDM4E (0.50) | GAA | |
| SCHEMBL15257915 | 0.62 | GRM5 (0.36) | GRM5 | |
| SCHEMBL26538070 | 0.62 | MAPT (0.41) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619931-A | Aryl or heteroaryl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-09-10 | — | — | CN | disclosed |