SCHEMBL7749784

SCHEMBL7749784

COC(=O)C1=CCCCO1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 1/20 0.38
CHRM3 P20309 2/20 0.37
LMNA P02545 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
THRB P10828 1/20 0.36
CHRM1 P11229 1/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 1/20 0.36
MGLL Q99685 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
CA12 O43570 5/20 0.35
CA1 P00915 5/20 0.35
CA2 P00918 5/20 0.35
CA7 P43166 5/20 0.35
CA9 Q16790 5/20 0.35
CA14 Q9ULX7 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3105012 0.88
SCHEMBL28956960 0.80 GABRR1 (0.39) ALDH1A1KDM4EHPGDALOX12MAPK10
SCHEMBL6987997 0.80 L3MBTL1 (0.42) ALDH1A1KDM4ELMNAALOX15CA12
SCHEMBL11126262 0.78
SCHEMBL3526544 0.75
SCHEMBL29044988 0.74 HDAC6 (0.47) ALDH1A1HPGDALOX15HSD17B10CA12
SCHEMBL1938924 0.74
Water SCHEMBL29902372 0.74 HCAR2 (0.39)
SCHEMBL20909482 0.71 ALDH1A1 (0.55) ALDH1A1KDM4ELMNAHPGDALOX15
Trifluoroacetic Acid SCHEMBL8589471 0.70 HCAR2 (0.32) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103097354-A Substituted benzamide compounds GRUENENTHAL CHEMIE 2013-05-08 CN disclosed
EP-0848712-A4 DIHYDROPYRAN DERIVATIVES AS VIRAL NEURAMINIDASE INHIBITORS BIOTA SCIENT MANAGEMENT (AU) 2001-04-18 EP disclosed
EP-0848712-A1 DIHYDROPYRAN DERIVATIVES AS VIRAL NEURAMINIDASE INHIBITORS BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1998-06-24 EP disclosed
WO-1997006157-A1 DIHYDROPYRAN DERIVATIVES AS VIRAL NEURAMINIDASE INHIBITORS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 1997-02-20 WO disclosed