⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105012 | 0.76 | — | — | |
| SCHEMBL28500709 | 0.72 | NPSR1 (0.32) | — | |
| SCHEMBL28500710 | 0.72 | POLB (0.30) | — | |
| SCHEMBL2404922 | 0.71 | PTPN1 (0.33) | — | |
| SCHEMBL6128389 | 0.69 | — | — | |
| SCHEMBL24447 | 0.66 | — | — | |
| SCHEMBL7749784 | 0.66 | ALDH1A1 (0.38) | — | |
| SCHEMBL5889497 | 0.65 | SENP1 (0.47) | — | |
| SCHEMBL26103828 | 0.65 | MAPT (0.46) | — | |
| SCHEMBL19310541 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |