Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31050870 | 1.00 | POLB (0.38) | POLBL3MBTL1KDM4EPIM1MAPT | |
| SCHEMBL4406875 | 0.78 | KDM4E (0.42) | KDM4EMAPTKMT2ASQORLMNA | |
| SCHEMBL25330482 | 0.78 | SQOR (0.38) | POLBL3MBTL1KDM4EPIM1MAPT | |
| SCHEMBL17929423 | 0.78 | PIM1 (0.39) | KDM4EPIM1MAPTNPSR1MEN1 | |
| SCHEMBL15845854 | 0.77 | NPSR1 (0.49) | POLBL3MBTL1KDM4EPIM1MAPT | |
| SCHEMBL4953802 | 0.76 | CA2 (0.34) | PIM1MEN1KMT2ASQOR | |
| SCHEMBL9678358 | 0.76 | POLB (0.46) | POLBL3MBTL1MAPTNPSR1PRKDC | |
| SCHEMBL31050846 | 0.75 | P2RX3 (0.36) | POLBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL18112970 | 0.74 | MEN1 (0.44) | POLBL3MBTL1KDM4EMAPTNPSR1 | |
| SCHEMBL14782648 | 0.74 | MAPT (0.41) | L3MBTL1KDM4EPIM1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024169790-A1 | SULFOXIDE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2024-08-22 | — | — | WO | disclosed |