SCHEMBL31051287

SCHEMBL31051287

COC(=O)Nc1ccc(-c2cnc3c(C)cc(-c4nnc(C)n4-c4ccc(F)c(OC)c4)cn23)cn1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ OXTR P30559 2/20 0.35
▸ PAX8 Q06710 4/20 0.34
▸ FYN P06241 3/20 0.34
▸ RAD52 P43351 1/20 0.34
▸ ABCB1 P08183 2/20 0.34
▸ ABCC1 P33527 1/20 0.34
▸ HDAC3 O15379 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HDAC6 Q9UBN7 1/20 0.34
▸ POLQ O75417 1/20 0.33
▸ MC4R P32245 2/20 0.33
▸ TTK P33981 1/20 0.33
▸ PDE4B Q07343 1/20 0.33
▸ AVPR2 P30518 1/20 0.33
▸ AVPR1A P37288 1/20 0.33
▸ IGF1R P08069 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31051210 0.93 MC4R (0.34) OXTRFYNMC4R
SCHEMBL27399497 0.93 MC4R (0.34) OXTRFYNMC4R
SCHEMBL31051200 0.90 OXTR (0.41) OXTRPAX8FYNRAD52ABCB1
SCHEMBL27399706 0.90 OXTR (0.41) OXTRPAX8FYNRAD52ABCB1
SCHEMBL27399671 0.90 FYN (0.40) OXTRPAX8FYNAVPR1A
SCHEMBL31051179 0.90 FYN (0.40) OXTRPAX8FYNAVPR1A
SCHEMBL31051298 0.89 PIK3CA (0.41) OXTRFYNABCB1ABCC1POLQ
SCHEMBL31051296 0.89 PIK3CA (0.41) OXTRFYNABCB1ABCC1POLQ
SCHEMBL31051255 0.87 TUBB4A (0.35) PAX8FYNRAD52ABCB1ABCC1
SCHEMBL31051199 0.86 PAX8 (0.34) PAX8FYNRAD52ABCB1ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634178-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-22 — — EP disclosed
WO-2024126404-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 — — WO disclosed
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