SCHEMBL7732435

SCHEMBL7732435

[CH2]CCCCCCCCCc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
HRH1 P35367 1/20 0.47
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CHRM2 P08172 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1611161 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL11403376 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1610894 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL6317614 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1119421 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1119390 0.98 IGF1R (0.53) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1119426 0.91 CYP1A2 (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL22092404 0.88 CYP1A2 (0.50) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL10571160 0.88 IGF1R (0.61) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL6546754 0.85 IGF1R (0.64) IGF1RALOX15CYP1A2CYP2A6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680495-B1 STRUCTURED COPOLYMERS USED AS CARRIERS OF METAL IONS DOW CHEMICAL CO (US) 2002-08-07 EP claimed
EP-0680498-B1 SMALL CELL FOAMS AND BLENDS AND A PROCESS FOR THEIR PREPARATION DOW CHEMICAL CO (US) 1997-12-03 EP claimed
US-5560929-A DENSE STAR POLYMERS CHELATED WITH A METAL COMPOUND HAVING A END GROUP TO PROVIDE A HYDROPHOBIC OUTER SHELL; METAL EXTRACTION; WATER PURIFICATION; RECOVERING PRECIOUS METALS THE DOW CHEMICAL COMPANY (US) 1996-10-01 US claimed
EP-0680495-A1 STRUCTURED COPOLYMERS USED AS ABSORBENTS, GELS AND CARRIERS OF METAL IONS THE DOW CHEMICAL COMPANY (US) 1995-11-08 EP claimed
WO-1994017125-A1 STRUCTURED COPOLYMERS USED AS ABSORBENTS, GELS AND CARRIERS OF METAL IONS THE DOW CHEMICAL COMPANY (US) 1994-08-04 WO claimed
EP-0680495-B1 STRUCTURED COPOLYMERS USED AS CARRIERS OF METAL IONS DOW CHEMICAL CO (US) 2002-08-07 EP disclosed
EP-0680498-B1 SMALL CELL FOAMS AND BLENDS AND A PROCESS FOR THEIR PREPARATION DOW CHEMICAL CO (US) 1997-12-03 EP disclosed
US-5560929-A DENSE STAR POLYMERS CHELATED WITH A METAL COMPOUND HAVING A END GROUP TO PROVIDE A HYDROPHOBIC OUTER SHELL; METAL EXTRACTION; WATER PURIFICATION; RECOVERING PRECIOUS METALS THE DOW CHEMICAL COMPANY (US) 1996-10-01 US disclosed
EP-0680498-A1 SMALL CELL FOAMS AND BLENDS AND A PROCESS FOR THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1995-11-08 EP disclosed
EP-0680495-A1 STRUCTURED COPOLYMERS USED AS ABSORBENTS, GELS AND CARRIERS OF METAL IONS THE DOW CHEMICAL COMPANY (US) 1995-11-08 EP disclosed
US-5393795-A Polymer blend containing a modified dense star polymer or dendrimer and a matrix polymer THE DOW CHEMICAL COMPANY (US) 1995-02-28 US disclosed
US-5393797-A Small cell foams containing a modified dense star polymer or dendrimer as a nucleating agent THE DOW CHEMICAL COMPANY (US) 1995-02-28 US disclosed
US-5387617-A Small cell foams and blends and a process for their preparation THE DOW CHEMICAL COMPANY (US) 1995-02-07 US disclosed
WO-1994017125-A1 STRUCTURED COPOLYMERS USED AS ABSORBENTS, GELS AND CARRIERS OF METAL IONS THE DOW CHEMICAL COMPANY (US) 1994-08-04 WO disclosed
WO-1994017130-A1 SMALL CELL FOAMS AND BLENDS AND A PROCESS FOR THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1994-08-04 WO disclosed
US-4282171-A Phosphorus and sulfur containing amides and thioamides THE LUBRIZOL CORPORATION (US) 1981-08-04 US disclosed
US-4208357-A Process for preparing phosphorus and sulfur containing amides and thioamides THE LUBRIZOL CORPORATION (US) 1980-06-17 US disclosed
US-4081386-A ANTIOXIDANTS THE LUBRIZOL CORPORATION (US) 1978-03-28 US disclosed
US-4032461-A PHOSPHORUS AND SULFUR CONTAINING AMIDES AND THIOAMIDES AS LUBRICATING OIL ADDITIVES AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1977-06-28 US disclosed