Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051779 | 0.87 | DRD2 (0.40) | ALDH1A1LMNADRD2DRD3HTR2A | |
| SCHEMBL31051749 | 0.82 | DRD2 (0.44) | ALDH1A1LMNADRD2DRD3HTR2A | |
| SCHEMBL31051810 | 0.82 | DRD2 (0.61) | DRD2DRD3HTR2ADRD1SIGMAR1 | |
| SCHEMBL31052092 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNADRD2DRD3HTR2A | |
| SCHEMBL31051856 | 0.81 | DRD2 (0.65) | ALDH1A1LMNADRD2DRD3HTR2A | |
| SCHEMBL31052045 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNADRD2DRD3HTR2A | |
| SCHEMBL31052293 | 0.80 | ADRB1 (0.37) | ALDH1A1LMNAHTR2CADRB1MAPT | |
| SCHEMBL31051951 | 0.76 | ADRB1 (0.65) | ALDH1A1LMNAADRB1HTR1A | |
| SCHEMBL31052080 | 0.75 | DRD2 (0.63) | DRD2DRD3HTR2ADRD1SIGMAR1 | |
| SCHEMBL31051850 | 0.73 | DRD2 (0.55) | DRD2DRD3HTR2ADRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678188-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING, OR MANAGING BILIRUBIN-INDUCED NEUROLOGICAL DYSFUNCTION, PSYCHIATRIC DISORDERS ASSOCIATED WITH JAUNDICE, OR PSYCHIATRIC DISORDERS CAUSED BY BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS | Ohnishi, Arata (JP) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024185842-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING, OR MANAGING BILIRUBIN-INDUCED NEUROLOGICAL DYSFUNCTION, PSYCHIATRIC DISORDERS ASSOCIATED WITH JAUNDICE, OR PSYCHIATRIC DISORDERS CAUSED BY BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS | 国立大学法人島根大学 | 2024-09-12 | — | — | WO | disclosed |