Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.59 |
| ▸ | HTR6 | P50406 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | HTR3A | P46098 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052231 | 0.83 | DRD2 (0.49) | ADRB1HTR2ADRD2DRD1DRD3 | |
| SCHEMBL31052071 | 0.81 | HTR6 (0.41) | ADRB1HTR6HTR2C | |
| SCHEMBL31052204 | 0.81 | DRD2 (0.38) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL31052285 | 0.81 | ADRB1 (0.38) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL31051759 | 0.81 | ADRB1 (0.38) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL1455855 | 0.81 | ADRB1 (0.59) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL16703491 | 0.81 | ADRB1 (0.59) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL7808439 | 0.81 | ADRB1 (0.59) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL7815929 | 0.81 | ADRB1 (0.59) | ADRB1HTR6HTR2ADRD2DRD1 | |
| SCHEMBL31051835 | 0.81 | ADRB1 (0.59) | ADRB1HTR6HTR2ADRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678188-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING, OR MANAGING BILIRUBIN-INDUCED NEUROLOGICAL DYSFUNCTION, PSYCHIATRIC DISORDERS ASSOCIATED WITH JAUNDICE, OR PSYCHIATRIC DISORDERS CAUSED BY BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS | Ohnishi, Arata (JP) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024185842-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING, OR MANAGING BILIRUBIN-INDUCED NEUROLOGICAL DYSFUNCTION, PSYCHIATRIC DISORDERS ASSOCIATED WITH JAUNDICE, OR PSYCHIATRIC DISORDERS CAUSED BY BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS | 国立大学法人島根大学 | 2024-09-12 | — | — | WO | disclosed |