Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25222940 | 1.00 | DHFR (0.42) | DHFRKDM4CNPC1RAB9APDGFRB | |
| SCHEMBL30542287 | 0.83 | KDM4C (0.51) | DHFRKDM4CNPC1RAB9APDGFRB | |
| SCHEMBL6825236 | 0.83 | DHFR (0.42) | DHFRKDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL6824651 | 0.83 | DHFR (0.42) | DHFRKDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL30542278 | 0.79 | DHFR (0.43) | DHFRKDM4CNPC1RAB9APDGFRB | |
| SCHEMBL25217625 | 0.78 | DHFR (0.37) | DHFRKDM4CNPC1RAB9APDGFRB | |
| SCHEMBL30542268 | 0.78 | DHFR (0.37) | DHFRKDM4CNPC1RAB9APDGFRB | |
| SCHEMBL5897 | 0.75 | TNK2 (0.40) | DHFRKDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL2894278 | 0.74 | DHFR (0.42) | DHFRKDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL17280983 | 0.74 | CHRNB2 (0.40) | DHFRKDM4CNPC1RAB9ATNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525020-A | Compound with CLK and DYRK inhibiting activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-08-20 | — | — | CN | disclosed |