Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926462 | 0.82 | KDM4C (0.39) | DHFRKDM4CNPC1RAB9AHSD11B1 | |
| SCHEMBL13577642 | 0.82 | DHFR (0.38) | DHFRKDM4CNPC1RAB9AHSD11B1 | |
| SCHEMBL15884393 | 0.81 | KDM4C (0.49) | CHRNB2CHRNA4DHFRKDM4CNPC1 | |
| SCHEMBL30542315 | 0.81 | KDM4C (0.49) | CHRNB2CHRNA4DHFRKDM4CNPC1 | |
| SCHEMBL25223911 | 0.78 | DHFR (0.45) | CHRNB2CHRNA4DHFRKDM4CNPC1 | |
| SCHEMBL31052321 | 0.78 | DHFR (0.47) | CHRNB2CHRNA4DHFRKDM4CNPC1 | |
| SCHEMBL31052157 | 0.78 | DHFR (0.45) | CHRNB2CHRNA4DHFRKDM4CNPC1 | |
| SCHEMBL25260740 | 0.78 | DHFR (0.47) | CHRNB2CHRNA4DHFRKDM4CNPC1 | |
| SCHEMBL16518357 | 0.77 | KDM4C (0.34) | DHFRKDM4CNPC1RAB9AHSD11B1 | |
| SCHEMBL5849238 | 0.77 | CHRNB2 (0.46) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | ESR1, EPX, SDHB | CHRNB2 466/4885CHRNA4 671/4885DHFR 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.