Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25222858 | 1.00 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1FGFR4PKMHTR6 | |
| SCHEMBL31052350 | 0.87 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1PKMHTR6ACVR1 | |
| SCHEMBL31052268 | 0.86 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1FGFR4PKMHTR6 | |
| SCHEMBL25256633 | 0.86 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1FGFR4PKMHTR6 | |
| SCHEMBL31052300 | 0.79 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1PKMHTR6ACVR1 | |
| SCHEMBL25273851 | 0.75 | L3MBTL1 (0.45) | L3MBTL1HTR6ACVR1 | |
| SCHEMBL31052234 | 0.75 | L3MBTL1 (0.45) | L3MBTL1HTR6ACVR1 | |
| SCHEMBL25273685 | 0.74 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1PKMHTR6ACVR1 | |
| SCHEMBL31052395 | 0.74 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1PKMHTR6ACVR1 | |
| SCHEMBL25219192 | 0.72 | CNR2 (0.40) | ALDH1A1HTR6LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525020-A | Compound with CLK and DYRK inhibiting activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-08-20 | — | — | CN | disclosed |