Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017371 | 0.88 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31052340 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30349320 | 0.83 | SMN1; SMN2 (0.38) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25158073 | 0.83 | SMN1; SMN2 (0.38) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1016690 | 0.83 | YTHDC1 (0.41) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL25221204 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31052310 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30407960 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18394254 | 0.81 | RAPGEF4 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30120753 | 0.80 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525020-A | Compound with CLK and DYRK inhibiting activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-08-20 | — | — | CN | disclosed |