Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466464 | 0.92 | CXCL8 (0.39) | CXCL8AKR1B1TSHRTHRBPKM | |
| SCHEMBL248156 | 0.83 | RXRA (0.41) | CXCL8AKR1B1TSHRTHRBPTGS1 | |
| SCHEMBL332576 | 0.83 | CXCL8 (0.43) | CXCL8AKR1B1TSHRPKMMEN1 | |
| SCHEMBL29362137 | 0.83 | CXCL8 (0.43) | CXCL8AKR1B1TSHRPKMMEN1 | |
| SCHEMBL31125275 | 0.82 | AKR1B1 (0.44) | CXCL8AKR1B1TSHRTHRBMEN1 | |
| SCHEMBL4314806 | 0.82 | KIF11 (0.36) | HDAC1HDAC8 | |
| SCHEMBL29140954 | 0.81 | CXCL8 (0.42) | CXCL8AKR1B1TSHRPKMMEN1 | |
| SCHEMBL30734413 | 0.81 | CXCL8 (0.42) | CXCL8AKR1B1TSHRPKMMEN1 | |
| SCHEMBL22775478 | 0.81 | AKR1B1 (0.42) | CXCL8AKR1B1TSHRTHRBMEN1 | |
| SCHEMBL29431223 | 0.81 | AKR1B1 (0.42) | CXCL8AKR1B1TSHRTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496142-A | Aryl alkylamine compound and preparation method and application thereof | 仁合益康集团有限公司 | 2024-08-16 | — | — | CN | disclosed |