Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 19/20 | 0.59 |
| ▸ | THRB | P10828 | 19/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486074 | 0.88 | THRA (0.60) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL31054370 | 0.88 | THRA (0.54) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22660335 | 0.81 | THRA (0.48) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL31054376 | 0.81 | THRB (0.46) | THRATHRB | |
| SCHEMBL31054391 | 0.76 | THRA (0.55) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22668214 | 0.75 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL2927006 | 0.74 | THRB (1.00) | THRATHRB | |
| SCHEMBL14628110 | 0.74 | THRA (0.83) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL31054372 | 0.74 | THRB (0.58) | THRATHRB | |
| SCHEMBL28486073 | 0.71 | THRA (0.56) | THRATHRBCYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290483-A | Pyridazinone compound and application thereof | 烟台药物研究所 | 2024-07-05 | — | — | CN | disclosed |