Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.38 |
| ▸ | THRB | P10828 | 14/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660386 | 0.87 | THRA (0.41) | THRATHRB | |
| SCHEMBL30398362 | 0.87 | THRA (0.41) | THRATHRB | |
| SCHEMBL31054367 | 0.85 | THRA (0.36) | THRATHRBGABRA1GABRB1 | |
| SCHEMBL2923676 | 0.80 | THRB (0.63) | THRATHRB | |
| SCHEMBL38660363 | 0.79 | THRB (0.40) | THRATHRBLMNA | |
| SCHEMBL22632552 | 0.79 | THRB (0.40) | THRATHRBLMNA | |
| SCHEMBL2926178 | 0.79 | THRA (0.49) | THRATHRB | |
| SCHEMBL31054368 | 0.77 | THRA (0.33) | THRATHRB | |
| SCHEMBL24548618 | 0.76 | THRB (0.36) | THRATHRBLMNAADRA1A | |
| SCHEMBL2923821 | 0.75 | THRB (0.69) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290483-A | Pyridazinone compound and application thereof | 烟台药物研究所 | 2024-07-05 | — | — | CN | disclosed |