Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903950 | 1.00 | CHUK (0.38) | CHUKLMNAKDM4ECYP3A4CYP1A2 | |
| SCHEMBL27192425 | 0.81 | CYP3A4 (0.39) | LMNAKDM4ECYP3A4CYP1A2CYP2D6 | |
| SCHEMBL26933317 | 0.74 | AGTR1 (0.40) | KDM4ECYP3A4HTTKMT2APOLB | |
| SCHEMBL29890282 | 0.74 | AGTR1 (0.40) | KDM4ECYP3A4HTTKMT2APOLB | |
| SCHEMBL14658340 | 0.74 | ADRA2A (0.39) | LMNAKDM4ECYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27191763 | 0.71 | AGTR1 (0.40) | KDM4ECYP1A2HTTALDH1A1HPGD | |
| SCHEMBL27191730 | 0.70 | ESR1 (0.36) | L3MBTL1ESR1ESR2 | |
| SCHEMBL7538490 | 0.70 | CYP3A4 (0.37) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL26933268 | 0.70 | IMPDH2 (0.36) | KDM4EIMPDH2ALDH1A1KMT2APOLB | |
| SCHEMBL20856359 | 0.69 | HTT (0.42) | CHUKLMNAKDM4ECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877364-B1 | ROCK KINASE INHIBITORS | Cervello Therapeutics LLC (US) | 2024-08-21 | — | — | EP | disclosed |