Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26975367 | 0.90 | NLRP3 (0.42) | NLRP3GSTO1ALDH1A1TSHR | |
| SCHEMBL22460158 | 0.89 | GSTO1 (0.41) | NLRP3GSTO1ALDH1A1TSHR | |
| SCHEMBL31055711 | 0.87 | NLRP3 (0.47) | NLRP3GSTO1 | |
| SCHEMBL31055699 | 0.87 | NLRP3 (0.47) | NLRP3GSTO1 | |
| SCHEMBL26975368 | 0.86 | NLRP3 (0.50) | NLRP3 | |
| SCHEMBL31055707 | 0.85 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL31055693 | 0.84 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL22460320 | 0.83 | GAA (0.52) | NLRP3 | |
| SCHEMBL31055732 | 0.83 | NLRP3 (0.47) | NLRP3GSTO1 | |
| SCHEMBL31055695 | 0.81 | NLRP3 (0.48) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |