Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056675 | 0.81 | NPC1 (0.32) | NPC1 | |
| SCHEMBL31056295 | 0.80 | DGAT1 (0.31) | — | |
| SCHEMBL25395444 | 0.77 | TSHR (0.34) | L3MBTL1OPRK1KDM4ETSHRHSD17B10 | |
| SCHEMBL29495175 | 0.77 | TSHR (0.34) | L3MBTL1OPRK1KDM4ETSHRHSD17B10 | |
| SCHEMBL31056181 | 0.77 | MAPK1 (0.35) | L3MBTL1MAPTOPRK1KDM4ETSHR | |
| SCHEMBL31056317 | 0.76 | — | — | |
| SCHEMBL15917685 | 0.74 | DGAT1 (0.35) | L3MBTL1ALDH1A1MAPTOPRK1KDM4E | |
| SCHEMBL30938860 | 0.74 | PTGER4 (0.36) | NPC1ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL1592506 | 0.73 | KMT2A (0.37) | L3MBTL1ALDH1A1MAPTMEN1GAA | |
| SCHEMBL1592509 | 0.73 | KMT2A (0.37) | L3MBTL1ALDH1A1MAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |