Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25395444 | 0.80 | TSHR (0.34) | MAPK1DGAT1HSD17B10L3MBTL1TSHR | |
| SCHEMBL15917685 | 0.80 | DGAT1 (0.35) | DGAT1KMT2AHSD17B10L3MBTL1MAPT | |
| SCHEMBL29495175 | 0.80 | TSHR (0.34) | MAPK1DGAT1HSD17B10L3MBTL1TSHR | |
| SCHEMBL31056067 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL31056694 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL701543 | 0.77 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL31056157 | 0.77 | CSNK2A2 (0.32) | KMT2AKLKB1HSD17B10L3MBTL1MAPT | |
| SCHEMBL20604807 | 0.76 | HSD17B10 (0.34) | DGAT1KMT2AKLKB1HSD17B10L3MBTL1 | |
| SCHEMBL15973235 | 0.74 | L3MBTL1 (0.38) | HTTKMT2AHSD17B10L3MBTL1TSHR | |
| SCHEMBL31056032 | 0.73 | DGAT1 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |