Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25395444 | 1.00 | TSHR (0.34) | TSHRUSP2LMNADGAT1OPRK1 | |
| SCHEMBL29495203 | 0.89 | DGAT1 (0.34) | LMNADGAT1BRD4CREBBPACHE | |
| SCHEMBL22932790 | 0.89 | DGAT1 (0.34) | LMNADGAT1BRD4CREBBPACHE | |
| SCHEMBL31056179 | 0.85 | DGAT1 (0.33) | DGAT1BRD4CREBBP | |
| SCHEMBL22717531 | 0.82 | KDM4E (0.40) | TSHRUSP2LMNADGAT1BRD4 | |
| SCHEMBL30258024 | 0.80 | ACHE (0.44) | TSHRUSP2LMNAOPRK1ACHE | |
| SCHEMBL25262955 | 0.80 | ACHE (0.44) | TSHRUSP2LMNAOPRK1ACHE | |
| SCHEMBL31056181 | 0.80 | MAPK1 (0.35) | TSHRLMNADGAT1OPRK1MAPK1 | |
| SCHEMBL24501448 | 0.80 | USP2 (0.40) | TSHRUSP2LMNADGAT1BRD4 | |
| SCHEMBL30640065 | 0.80 | USP2 (0.40) | TSHRUSP2LMNADGAT1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |