Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932061 | 0.86 | ALDH1A1 (0.52) | APPALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL852240 | 0.84 | ALDH1A1 (0.59) | APPALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL8570827 | 0.83 | PTGER1 (0.56) | APPALDH1A1L3MBTL1NPC1CYP2C9 | |
| SCHEMBL31055984 | 0.83 | APP (0.52) | APPNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4480514 | 0.83 | APP (0.52) | APPALDH1A1L3MBTL1LMNANPC1 | |
| SCHEMBL2929421 | 0.83 | KDM4E (0.54) | APPALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL1648045 | 0.82 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBL3MBTL1LMNA | |
| SCHEMBL2290346 | 0.82 | TRPM8 (0.55) | APPNPC1HTTMEN1KMT2A | |
| SCHEMBL6805062 | 0.82 | ALDH1A1 (0.48) | APPALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL6234420 | 0.81 | ALDH1A1 (0.53) | APPALDH1A1KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |