SCHEMBL31056357

SCHEMBL31056357

C[Si](C)(C)CCOCn1ccc(C(F)F)n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31283459 0.84 F2RL1 (0.31) DGAT1
SCHEMBL24102105 0.84 NPC1 (0.31) DGAT1
SCHEMBL31283365 0.82 DGAT1 (0.30) DGAT1
SCHEMBL21380706 0.82 IRAK4 (0.34) DGAT1
SCHEMBL26910784 0.80
SCHEMBL31308722 0.80 DGAT1 (0.35) DGAT1
SCHEMBL22717364 0.78 KDM4E (0.34)
SCHEMBL3496820 0.78 DGAT1 (0.35) DGAT1
SCHEMBL20744490 0.76 DGAT1 (0.40) DGAT1
SCHEMBL401354 0.76 ALDH1A1 (0.39) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024178390-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2024-08-29 WO disclosed