Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324954 | 1.00 | TDP1 (0.50) | TDP1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL31056870 | 0.83 | ALDH1A1 (0.48) | TDP1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL481659 | 0.83 | ALOX5AP (0.49) | TDP1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL29324953 | 0.83 | ALDH1A1 (0.48) | TDP1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL29598250 | 0.81 | MAPK1 (0.61) | TDP1KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL4469903 | 0.81 | TDP1 (0.59) | TDP1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL31145166 | 0.81 | TDP1 (0.59) | TDP1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL15599290 | 0.78 | ABL1 (0.43) | TDP1ALDH1A1MAPK1ABL1SMN1; SMN2 | |
| SCHEMBL17687665 | 0.78 | KDM4E (0.53) | TDP1KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL18818444 | 0.77 | CA1 (0.59) | TDP1KDM4EALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |