Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324953 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL29324954 | 0.83 | TDP1 (0.50) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL31056701 | 0.83 | TDP1 (0.50) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL481659 | 0.81 | ALOX5AP (0.49) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL2952102 | 0.81 | MAPT (0.51) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL2952147 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL38659193 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL29598250 | 0.80 | MAPK1 (0.61) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL836841 | 0.80 | MAPK1 (0.49) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL4412321 | 0.78 | MAPT (0.55) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |