Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056032 | 0.83 | DGAT1 (0.32) | — | |
| SCHEMBL31056658 | 0.82 | KLKB1 (0.34) | NPC1KLKB1 | |
| SCHEMBL31056438 | 0.82 | KLKB1 (0.32) | NPC1KLKB1 | |
| SCHEMBL31056189 | 0.79 | NPC1 (0.32) | NPC1KLKB1 | |
| SCHEMBL31055961 | 0.77 | NPC1 (0.37) | NPC1KLKB1 | |
| SCHEMBL31562732 | 0.69 | NPC1 (0.32) | NPC1KLKB1 | |
| SCHEMBL23193770 | 0.67 | HCAR3 (0.51) | HCAR3NPC1 | |
| SCHEMBL29974610 | 0.67 | HCAR3 (0.51) | HCAR3NPC1 | |
| SCHEMBL19358773 | 0.66 | HCAR3 (0.37) | HCAR3NPC1 | |
| SCHEMBL31056181 | 0.66 | MAPK1 (0.35) | HCAR3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |