Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424094 | 0.89 | ALDH1A1 (0.46) | CYP2C9ALDH1A1ALOX15LMNAHPGD | |
| SCHEMBL15203701 | 0.86 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15ABCC1CYP2D6 | |
| SCHEMBL30109175 | 0.86 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15ABCC1CYP2D6 | |
| SCHEMBL28789929 | 0.84 | PARP1 (0.43) | CYP2C9ALDH1A1ALOX15MEN1CYP2D6 | |
| SCHEMBL28452039 | 0.84 | PARP1 (0.43) | CYP2C9ALDH1A1ALOX15MEN1CYP2D6 | |
| SCHEMBL4878097 | 0.80 | HTR2C (0.53) | CYP2C9ALDH1A1ALOX15SLC18A3SIGMAR1 | |
| SCHEMBL31056773 | 0.77 | CYP2C9 (0.40) | CYP2C9ALDH1A1ALOX15CYP2D6KMT2A | |
| SCHEMBL10651485 | 0.76 | ALDH1A1 (0.48) | CYP2C9ALDH1A1ALOX15LMNAHPGD | |
| SCHEMBL31056868 | 0.76 | CYP2C9 (0.39) | CYP2C9ALDH1A1ALOX15MEN1LMNA | |
| Phthalic Acid SCHEMBL5874844 | 0.75 | ALDH1A1 (0.70) | ALDH1A1ALOX15SIGMAR1ABCC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |