Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109175 | 0.77 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15SMN1; SMN2MAPT | |
| SCHEMBL15203701 | 0.77 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15SMN1; SMN2MAPT | |
| SCHEMBL31424094 | 0.76 | ALDH1A1 (0.46) | CYP2C9ALDH1A1ALOX15SMN1; SMN2MAPT | |
| SCHEMBL6268350 | 0.76 | PRCP (0.46) | ALDH1A1SMN1; SMN2MAPTLMNANPSR1 | |
| SCHEMBL31056764 | 0.76 | CYP2C9 (0.41) | CYP2C9ALDH1A1ALOX15SMN1; SMN2LMNA | |
| SCHEMBL28789929 | 0.75 | PARP1 (0.43) | CYP2C9ALDH1A1ALOX15HPGDRAB9A | |
| SCHEMBL28452039 | 0.75 | PARP1 (0.43) | CYP2C9ALDH1A1ALOX15HPGDRAB9A | |
| SCHEMBL10651485 | 0.74 | ALDH1A1 (0.48) | CYP2C9ALDH1A1ALOX15SMN1; SMN2MAPT | |
| SCHEMBL31056773 | 0.72 | CYP2C9 (0.40) | CYP2C9ALDH1A1ALOX15NPSR1TSHR | |
| SCHEMBL10648168 | 0.69 | CYP2C9 (0.42) | CYP2C9ALDH1A1ALOX15SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |