Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109175 | 0.91 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15CHRNB2CHRNB4 | |
| SCHEMBL15203701 | 0.91 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15CHRNB2CHRNB4 | |
| SCHEMBL28452039 | 0.83 | PARP1 (0.43) | CYP2C9ALDH1A1ALOX15CHRNB2CHRNA4 | |
| SCHEMBL28789929 | 0.83 | PARP1 (0.43) | CYP2C9ALDH1A1ALOX15CHRNB2CHRNA4 | |
| SCHEMBL10648168 | 0.83 | CYP2C9 (0.42) | CYP2C9ALDH1A1ALOX15TSHRNPSR1 | |
| SCHEMBL31056891 | 0.78 | PARP1 (0.44) | CYP2C9ALDH1A1ALOX15PARP1KMT2A | |
| SCHEMBL31424094 | 0.77 | ALDH1A1 (0.46) | CYP2C9ALDH1A1ALOX15PARP1TSHR | |
| SCHEMBL3254494 | 0.77 | PARP1 (0.55) | ALDH1A1PARP1TSHRRPS6KB1 | |
| SCHEMBL31056764 | 0.77 | CYP2C9 (0.41) | CYP2C9ALDH1A1ALOX15PARP1KMT2A | |
| SCHEMBL16446714 | 0.77 | PARP1 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |