Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109175 | 0.86 | PARP1 (0.44) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL15203701 | 0.86 | PARP1 (0.44) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5863841 | 0.81 | PARP1 (0.41) | PARP1ALDH1A1HPGDCDC25BCASP6 | |
| SCHEMBL27977978 | 0.80 | PARP1 (0.40) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30109198 | 0.78 | ALDH1A1 (0.46) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL31056773 | 0.78 | CYP2C9 (0.40) | PARP1ALDH1A1PRKCGPRKCBPRKCA | |
| SCHEMBL30109265 | 0.76 | PARP1 (0.40) | PARP1CDC25BCYP2C9 | |
| SCHEMBL3254494 | 0.76 | PARP1 (0.55) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11300941 | 0.73 | KDM4C (0.39) | PARP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL31056764 | 0.73 | CYP2C9 (0.41) | PARP1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |