Cyclohexane

Cyclohexane

SCHEMBL3105735

C1CCCCC1.O=S(=O)(Cl)Cl

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.33
CA2 P00918 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL365424 1.00
Cyclooctane SCHEMBL27515472 1.00 CA1 (0.33) CA1CA2POLBTSHRKMT2A
Cyclopentane SCHEMBL2198075 1.00 CA1 (0.33) CA1CA2POLBTSHRKMT2A
SCHEMBL11357022 1.00
SCHEMBL254 0.82
SCHEMBL6681816 0.82
SCHEMBL9540531 0.82
SCHEMBL27986358 0.82 CA5A (0.33) CA1CA2CA7
Cyclopropane SCHEMBL28876799 0.80
Cyclohexane SCHEMBL11777586 0.80 CA5A (0.42) CA1CA2POLBTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116328564-A Method for preparing composite reverse osmosis membrane, composite reverse osmosis membrane prepared by method and application of composite reverse osmosis membrane 沃顿科技股份有限公司 2023-06-27 CN claimed
CN-116120261-A Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound 浙大宁波理工学院 2023-05-16 CN claimed
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US disclosed
US-12486253-B2 Therapeutics for the degradation of mutant BRAF C4 THERAPEUTICS, INC. (US) 2025-12-02 US disclosed
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP disclosed
CN-119977980-A Novel modulators of 5-hydroxytryptamine receptor 7 and methods of use thereof 英联邦高等教育系统坦普尔大学 2025-05-13 CN disclosed
CN-119998964-A Self-poisoning lithium secondary battery 辉能科技股份有限公司 2025-05-13 CN disclosed
US-20250115580-A1 THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF C4 THERAPEUTICS, INC. (US) 2025-04-10 US disclosed
CN-119768942-A Self-poisoning lithium secondary battery 辉能科技股份有限公司 2025-04-04 CN disclosed
CN-110177776-B Novel modulators of 5-hydroxytryptamine receptor 7 and methods of use thereof 英联邦高等教育系统坦普尔大学 2025-02-28 CN disclosed
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
US-5795892-A ANTICOAGULANTS BOEHRINGER MANNEIM GMBH (DE) 1998-08-18 US disclosed
EP-0805159-A1 Phosphorus containing alkyl or arylsulphonyl derivatives and method for preparing same Cytec Canada Inc. (CA) 1997-11-05 EP disclosed
US-4912231-A Reacting a proline derivative with an aromatic nucleophile in presence of a Lewis acid catalyst E. R. SQUIBB & SONS, INC. (US) 1990-03-27 US disclosed
US-4150051-A N-Cyanosulfonamide compounds CIBA-GEIGY CORPORATION (US) 1979-04-17 US disclosed
US-4080483-A COATINGS, MOLDING MATERIALS, LAMINATION CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4075185-A ADDITION POLYMERIZATION CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed
US-4072584-A PIGMENTS, RUBBER ALLIED CHEMICAL CORPORATION (US) 1978-02-07 US disclosed
US-4049711-A POLYSULFONAMIDE MONOMERS CIBA-GEIGY CORPORATION (US) 1977-09-20 US disclosed
US-3944526-A N-cyanosulfonamide resins and intermediates therefor and products thereof CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630529-B2 GCN2 modulator compounds NR3C1, GCN1, EIF2AK4 CA1 3553/4885CA2 1341/4885POLB 3713/4885
US-12486253-B2 Therapeutics for the degradation of mutant BRAF BRAF, NRAS, KRAS CA1 4783/4885CA2 4314/4885POLB 1018/4885
US-20250115580-A1 THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF BRAF, NRAS, KRAS CA1 4783/4885CA2 4314/4885POLB 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.