Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 15/20 | 0.81 |
| ▸ | SHMT2 | P34897 | 12/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255575 | 0.89 | SHMT1 (1.00) | SHMT1SHMT2EGLN1 | |
| SCHEMBL31057912 | 0.84 | SHMT1 (0.74) | SHMT1SHMT2EGLN1 | |
| SCHEMBL20255873 | 0.84 | SHMT1 (0.77) | SHMT1SHMT2EGLN1 | |
| SCHEMBL20255970 | 0.81 | SHMT1 (1.00) | SHMT1SHMT2EGLN1 | |
| SCHEMBL31057889 | 0.81 | SHMT1 (0.69) | SHMT1SHMT2EGLN1 | |
| SCHEMBL31057961 | 0.80 | SHMT1 (0.68) | SHMT1SHMT2EGLN1 | |
| SCHEMBL20255498 | 0.80 | SHMT2 (0.70) | SHMT1SHMT2EGLN1 | |
| SCHEMBL20255674 | 0.80 | SHMT2 (0.69) | SHMT1SHMT2EGLN1 | |
| SCHEMBL21560035 | 0.79 | SHMT1 (1.00) | SHMT1SHMT2EGLN1 | |
| SCHEMBL30163381 | 0.79 | SHMT1 (1.00) | SHMT1SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173718-A2 | HETEROBIFUNCTIONAL BINDERS OF KLHDC2 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2024-08-22 | — | — | WO | disclosed |