Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534129 | 0.81 | ESR1 (0.34) | ESR2ESR1OPRD1 | |
| SCHEMBL28313912 | 0.75 | OPRM1 (0.39) | MEN1KMT2A | |
| SCHEMBL1682719 | 0.74 | ESR2 (0.47) | ESR2ESR1MEN1KMT2ALMNA | |
| SCHEMBL15717660 | 0.73 | ESR2 (0.71) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL4450591 | 0.71 | ESR2 (0.74) | ESR2ESR1MEN1KMT2ALMNA | |
| SCHEMBL1284295 | 0.71 | ESR1 (0.38) | ESR2ESR1MEN1KMT2AMAPT | |
| SCHEMBL17653851 | 0.70 | ESR2 (0.43) | ESR2ESR1MEN1KMT2ALMNA | |
| SCHEMBL12336908 | 0.69 | ESR2 (0.78) | ESR2ESR1MEN1KMT2ALMNA | |
| SCHEMBL15275550 | 0.68 | ESR2 (0.83) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL6932651 | 0.68 | ESR2 (0.57) | ESR2ESR1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635942-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Carephar Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024152743-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏柯菲平医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |