Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253153 | 1.00 | LMNA (0.55) | LMNAABCB1TPMTMAPTHTT | |
| SCHEMBL290542 | 0.83 | LMNA (0.69) | LMNATPMTMAPTHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL29142671 | 0.81 | LMNA (0.67) | LMNATPMTMAPTHTTALDH1A1 | |
| SCHEMBL24253152 | 0.81 | LMNA (0.49) | LMNATPMTMAPTHTTALDH1A1 | |
| SCHEMBL1928259 | 0.78 | LMNA (0.62) | LMNATPMTMAPTHTTALDH1A1 | |
| SCHEMBL11808062 | 0.77 | LMNA (0.52) | LMNATPMTHTTALDH1A1KMT2A | |
| SCHEMBL10804813 | 0.77 | ALDH1A1 (0.51) | LMNATPMTMAPTALDH1A1KMT2A | |
| SCHEMBL12245712 | 0.77 | TPMT (0.73) | LMNATPMTMAPTHTTKMT2A | |
| Chloroform SCHEMBL7815652 | 0.77 | LMNA (0.60) | LMNATPMTMAPTHTTALDH1A1 | |
| SCHEMBL786462 | 0.77 | LMNA (0.60) | LMNATPMTMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388357-A | Heteroatom-containing chalcone derivative and preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-07-26 | — | — | CN | disclosed |